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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f2190ef6e3c0d9c10bc21c4ca5313eb8471c9823b023b6bf4113c5374d6c627' 
  AND token = 'sZioVN8ZtYAHSHQzxGWBw0Plub42xyVY8RING3qxJGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}