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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '332b5894ed481eba8fef5e94e8aa739bd3ffb12a8a1e5620807edeaf2c852523' 
  AND token = 'kW4FDAMjwdEBCVTuAMu+mN8CEGvtgVqcWgU8SfP8uqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}