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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c496de9f9def6741dffc53e7c225b0162d2b80d01c82e403a9f191c1b36a09a7' 
  AND token = 'mzYj2OLHXmZ/qF0fuo31cGxiV59bmERumFnCD2p2J+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}