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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0dd3f8254911f39cbdb5902632f58ad5bce03cda9287b2829dc4409ffc735008' 
  AND token = 'm1UiM7Q+Ezr+UqkH0VdzMqVvnzLvPrvqYILkKE8cbYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}