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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '074b9b790d6899ede8bac7b162ea64a0000339e1a8a4ab4104864d3224de5638' 
  AND token = 'PKMlIq0MkD7Tzwmuki34VVykD7LwSVEL8Z0eyzGlJEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}