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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '775486348fe0cbe443e5c80b02ea2ac2bffe14d955002fb5540d9e72ca7f1ffd' 
  AND token = 'HswjJtvAtqMBJIAsMOGKFHhyqUW5x4R6inan65EVnMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}