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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a45c4a5955d71b21fecec70732ff480e2b20975f27a888aeb334ba861288d73' 
  AND token = '4YCO94vKxwy7zV0lSqreUTWeVEuViTDpoNfWmyC0grQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}