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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '462b449274854a34c16044edf94ff005d9449a92537ab77c9fd903a531d42558' 
  AND token = 'gc2UsvAEgxL9/Bg5b6rz5Erc1kbcnfSn44dlOm1+OA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}