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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81d6e8482f7a9cb863e50b7f93a54072a7e891a7886ea79ec8c7fff23bdad79d' 
  AND token = 'yH+na1jkwgCwfQleUXTCPrjUark6UZ7Ef0GVQh+0F+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}