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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2138e40aa392e83d4297595852b96a80cf06ab03f18af0518ad8bd7f709a0175' 
  AND token = 'MC3cXcUM+vHhhRzerVtwMWk+XL/B5mffSBtQNS7Klfw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}