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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a7e05d1522d433a0dc2db5015083d81558577c18e0be14a5e349cb3382918da' 
  AND token = 'z3btkhCzp3Mw0rKgxc2RgwqS9ZeBcCyzv6uMVGnmxRo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}