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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0879ff296ca7154fe7f6589687e3465b10100396aa31384e24feeeb04dd374c3' 
  AND token = 'hY8i3VG0ttdBPQ+9CWrB34r0VtqhOzIjx1vL8dqrsuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}