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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65b50997c573ab9f32fb7d33b6474b6517c0370eb89dc6109bbb0475074be099' 
  AND token = '+SlCUIaLeowGRS0BSbaxgr65UfR8zlbhdraLBVot+9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}