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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff813c0fcad137d09cbda67e8881af53eef2bf37417a2c051cd28b214defe01f' 
  AND token = 'jq+NyE8EhPUcaD0RYCvaf6bylIgmsdBNzEwoBWn/YF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}