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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01a167d473f57ff6da3b995ece70729524ba60f08baa15257957a879f11c8dd9' 
  AND token = 'YfMRPymZutBf0Kde/JWhQatxGC2MA7NxzJiV0l/DBYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}