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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b29f5150f60fe3ecd30b58e01eb6099f8eb90544ec9231f4f3e35cdd8458e28' 
  AND token = 'SIF5QW7w/tPl75QN3edFMs/EDA8YiIe4m5/jGbpl6EI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}