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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '433c6c92f4979170862bec0df1cf2c7b7be2e4399b14fefb37859433b09629c7' 
  AND token = 'Eezh42aJqon/3HojDx6rtkPSoPEKXHKe0HdbvWyYtb8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}