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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1ff7b3a665045a55e5d9c9f257eab3b00a836cb9a960480868a3850f2a38fc9' 
  AND token = 'E9Ba6xu1ot6o/W51MmzyCUs1x/cjNjX8Ys90yzmJ8bo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}