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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9468649cef8bece7ef6470d10209b0fbc31cd5ac1d36d4e20a8239850400e87' 
  AND token = 'ySp/pXlYkiGNueabuaDBwQ5q8JEnlm54gRN2dd1ZPdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}