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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a48a699667e96f723b21bdb12517855872f863319dd65b2311a6178f0335e810' 
  AND token = 'hTot6KE2o5eV3sLygxqAbLd+0oVhmBGAuAFAour6VZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}