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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc159471bd043f5903282ce1a927b2ee6da4d95c8bd051d2022462a10400a8de' 
  AND token = 'NLyjBmtfQ0ekgIhGTLAk496wB+WAHElbiFmjq0slUoo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}