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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2645f9698414f6ab81e8f291a77987f8d73c29ed0c85d82cc0da9be4d21aede0' 
  AND token = '1vP7SXWhA1dICxu7ZbArdpQfkRLj8VAFmDRn/gtEhKU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}