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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa3726efe157da37ad08552783c59db1779dc4440ac327564bb5e3aa1540df3b' 
  AND token = 'YSBW2MmEJhanxBCEudBVkdXhyCG2gY/x0t4iUs1mIRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}