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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d990e0b997590394082f50c33b9eb606cb065de36daacc2f148ba8ebc847a8c' 
  AND token = 'GZVwvQTM6TObo5e+DZy91mICHnv5LSvlLzLQZW9+oNQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}