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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f73c0366ad6c5591df4d5ea186a9cf136ac1544c17fe2d956e2b53de0c278a7' 
  AND token = 'xMOX9HT7fWXvPYfRnEG0uji5VNk6Xb1z8G2Sf/bj1lg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}