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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c14f103214a91f68fd0a8ccc34c6f3bd142bffbea40501d18998401b86b5f59d' 
  AND token = 'k8cdQweQol/BgeaD2P1AF35v3bYC/d00FcJlWpiE3cM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}