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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86163522df259116a20bc1e5bd32f5a2e50427568b0e92c7939c12484c8847c6' 
  AND token = '1cP2TRR3Xgo0m0d9uQC51/zpIKFnY2PsJOuODm3lU3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}