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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd18578e2ba460ebd5841da1ec949bb0a82d68ce452f4f28fde58de8f41d94c9' 
  AND token = 'XFEUqQ5M7YHqf7sNfhecaSJ1J0KyFGIJhXS8V3KSSCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}