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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68b3be7c8dd0b38be2a455cfc358621ba4ae5bdcafcc8a7140437b456e8bfb06' 
  AND token = '7j6DjOF0pJeT/DZQ6cE0r0kdaNHgxhZUXbjAVLmrsc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}