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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6904d39a6275a83562631164781cce90ed27d895690898d5bf409c650980da2' 
  AND token = '1ZauxlfnQjfc02m4Biq4dfjMuooijRZZG//F2bH6iOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}