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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a94e6a14364e4688ba8bd43faa7622b59aa11fa20769f59c644d206cde2c5c2' 
  AND token = '29BB4uFQt35wX7Z5eOTPZqiake4795QSeWqtmPQLBWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}