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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f23e0ae390131e6239c3554915463686c42c89dd3020900f5a5eb45e9d568f4' 
  AND token = '2BbU++2mJck8/WWTmvEXe4de+Iv/wldWzYIXBo3fS+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}