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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6043cf201548f88e28e79109217bd4eb77d1be69640c3295d3711da5199f803c' 
  AND token = 'G9yc375yHxLlqOJRiVdAwIKOrHeLljEry2xkAa2ibIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}