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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12db7d2c0a6b729a38a1d5f71a80bb105f8df12c7cd5daa51848d4d84b2a55e3' 
  AND token = '3ufJdgAiTQMBou2lXYjj8W2tmBASd/ZbmctwWy2rPmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}