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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37ffdcc448daedf14bfef1c92a3d46e63c17a3f8bfb4a202a22c0b52cc35a8de' 
  AND token = 'MqHCqUGVHTrhRmQOE81CCrdYo66kIdYooKfn11UG1m8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}