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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bbb68e4a00079b4fd1d969700823fbd2728c50981af0c3e78a82aada551b038' 
  AND token = 'bIZI8p+iBI1aZ0tO/wOEoBz1yPGeWMyqfCi189rFYwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}