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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a307285af1ec7964852894d43715e4dcd768cb771a52f6427a5205554de82f7' 
  AND token = 'eHOc1X5qEpVvjHmzZe9DE4lxJEou9WPUC+wgv8v3mM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}