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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0c4fbf76df78d04b50b81db62ca09010fbcbbd09503832e7fd17bd78350edfe' 
  AND token = 'BE9UVR0nZzgi6jYu2jVic0lSQ2NNpTkJtHXVCwv3GoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}