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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0caf21f1cfa61c8c121c3cff2222eb4157542ebe09c2fc39f86e2f45e5b60089' 
  AND token = 'bti4dNjaT2MR2Jx5MC/uE0CtsaaYvQeR2JmN1uX/vpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}