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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59d5c785f771036dd7d060a6db3cd5d2777d567c84d373a69c9a8a7f6f077449' 
  AND token = 'WQBwxfoDAYI7u5RTVGlMNpC2XkeJFCDzgy4sYUkmkZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}