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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5737e5c9b39344c87b2a8b3a4002ed8ded08e0354b100b0b7b9b7af87b23bb43' 
  AND token = 'kPVat9kwOFP301CYaHU2mki22CxMe7t7pY/E1DxJ9BY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}