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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '257c0751d53dfc95e6a880d1d34c9be04451b01278a2674a59dcaec04e7e79f4' 
  AND token = 'qXx0Lxm8t6gSXo8V40YLHMqqMcnQsUlmO43Ff8dBJso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}