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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5d4a51c5a8b0be18f1fed30a38a23715adf4cdcdbed1c7b3ef7c2f10acb451d' 
  AND token = 'gUNytXbuO0pRPxz4cmOrYUCXD6IfNH5d2L3XYvq7uIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}