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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14082d3d263e918683a94ce2c84d448a58d76acbc46ed90f49cfcedf2c99ba2f' 
  AND token = 'Ry/ldlp0Q1p9XWCczuS8MfD+lB0c3V0HoDdLiwYejfY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}