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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78c159b85039154f119bdf5faeef6b76c19286e2f0475f621038ccf14fa45c48' 
  AND token = 'dNcVYjmJ0Vj2Q/CX42aIt8jdzZwT0/W2SJqxzE46YxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}