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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b12a36a6913aaf31645d75e856d69439efe2deb84686000a7c3fcf50403c18b7' 
  AND token = '3l0nXMKa0+IGKlUrtUnQTa0Wv8HSxzhFXwdJN2nJbrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}