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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'caebbcc7d1629722c7b56dfa88707d5a37568268f64a540ccc3df327af50e900' 
  AND token = 'lMkNddpQOM7hI59b1t2kNwcW8/q2MG/XBioPKQFyWJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}