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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40f38b4b100e38efbbb31806ff6ac2180791de346340feee7b6e5585c05dd0ac' 
  AND token = 'SXW6+8t7DFUi3xkfRomxch+yvj2UxoG2ChhTaWYecyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}