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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6af51356b554fc5758596b89f4e4e527072e500df9716b484e084005907a9db2' 
  AND token = 'eQJSqxdcTq609Y56o+ryR4uTdfwBRUBC6n/ZxKKmWbs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}