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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f22d7a19bbb74841e167c8835b4653f5b4f48f7b4fa2846d08e0e4353b0fe546' 
  AND token = 'soi4VELXJIXunLqQD21yo0beRHW9c9AoynGHtC0YcHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}